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作者简介
Gerhard Meisenberg, PhD, Course Director Medical Biochemistry, Ross University, Dominica, West Indies; and William H. Simmons, PhD, Course Director Medical Biochemistry, Strich School of Medicine, Loyola University, Maywood, IL 目录
Table of Contents
Part One:Principles of Molecular Structure and Function.
Chapter 1: Introduction to Biomolecules.
WATER: THE SOLVENT OF LIFE.
COVALENT BONDS AND NONCOVALENT INTERACTIONS
THE MAJOR CLASSES OF BIOMOLECULES.
Chapter 2: Protein structure.
THE AMINO ACIDS.
LEVELS OF PROTEIN STRUCTURE
THE PHYSICAL PROPERTIES OF PROTEINS
Chapter 3: Oxygen Transporters: Hemoglobin and Myoglobin.
Chapter 4: Enzymatic Reactions.
THERMODYNAMICS
ENZYME KINETICS
ENZYME INHIBITION
REACTION TYPES AND REACTION MECHANISMS
Chapter 5: Coenzymes
Part Two:Cell and Tissue Structure.
Chapter 6:Biological Membranes.
THE LIPID BILAYER.
MEMBRANE PROTEINS.
MEMBRANE TRANSPORT.
Chapter 7:The Cytoskeleton
Chapter 8:The Extracellular Matrix.
FIBROUS PROTEINS OF THE EXTRACELLULAR MATRIX.
THE AMORPHOUS GROUND SUBSTANCE
Part Three:Genetic Information:DNA, RNA, and Protein Synthesis.
Chapter 9:DNA, RNA, and Protein Synthesis:The Central Dogma of Molecular Biology.
DNA STRUCTURE AND DNA REPLICATION.
RNA AND THE GENETIC CODE.
PROTEIN SYNTHESIS.
REGULATION OF GENE EXPRESSION.
Chapter 10:Viruses
Chapter 11:The Human Genome and Its Expression.
CHROMATIN STRUCTURE.
THE ARCHITECTURE OF THE HUMAN GENOME.
TRANSCRIPTION AND TRANSLATION.
Chapter 12:The processing and targeting of proteins.
Chapter 13:Introduction to Genetic Diseases.
MUTATIONS AND DNA REPAIR.
THE HEMOGLOBINOPATHIES.
Chapter 14:DNA Technology.
THE TOOLS.
THE DIAGNOSIS OF GENETIC DISORDERS.
CLONING IN MICROORGANISMS.
GENE THERAPY.
Part Four:Signaling and signaling cascades.
Chapter 15:The Blood.
THE COMPONENTS OF PLASMA
PLASMA PROTEINS.
THE IMMUNOGLOBULINS.
THE BLOOD CLOTTING SYSTEM.
CLINICAL LABORATORY DIAGNOSIS.
Chapter 16:Extracellular Messengers.
THE STEROID HORMONES.
THE THYROID HORMONES.
THE BIOGENIC AMINES
PEPTIDES AND PROTEINS
THE EICOSANOIDS
NEUROTRANSMITTERS.
Chapter 17:Intracellular Messengers.
RECEPTORS.
G PROTEINS, SECOND MESSENGERS, AND PROTEIN KINASES.
RECEPTORS WITH ENZYMATIC ACTIVITIES.
Chapter 18:Cellular Growth Control and Cancer.
CELL CYCLE CONTROL.
MITOGENIC SIGNALING.
SOMATIC MUTATIONS AND CANCER.
SPECIFIC CANCERS.
Part Five:Metabolism.
Chapter 19:Digestive Enzymes.
Chapter 20:Introduction to Metabolism.
Chapter 21:The Oxidation of Glucose:Glycolysis, the TCA Cycle, and Oxidative Phosphorylation.
GLYCOLYSIS:FROM GLUCOSE TO PYRUVATE.
PYRUVATE DEHYDROGENASE AND THE TCA CYCLE:FROM PYRUVATE TO CARBON DIOXIDE AND REDUCED COENZYMES.
THE RESPIRATORY CHAIN AND OXIDATIVE PHOSPHORYLATION.
INHIBITION OF OXIDATIVE METABOLISM
Chapter 22:Carbohydrate Metabolism.
GLUCONEOGENEIS.
GLYCOGEN METABOLISM.
THE METABOLISM OF FRUCTOSE AND GALACTOSE.
THE MINOR PATHWAYS OF CARBOHYDRATE METABOLISM.
Chapter 23:The Metabolism of Fatty Acids and Triglycerides.
THE GENERATION OF METABOLIC ENERGY FROM FATTY ACIDS.
FROM CARBOHYDRATE TO FAT.
Chapter 24:The Metabolism of Membrane Lipids.
THE METABOLISM OF PHOSPHOGLYCERIDES AND SPHINGOLIPIDS.
CHOLESTEROL METABOLISM.
Chapter 25:Lipid Transport.
THE HIGHWAYS OF LIPID TRANSPORT.
LIPOPROTEINS AND ATHEROSCLEROSIS.
Chapter 26:Amino Acid Metabolism.
THE FATE OF THE AMINO NITROGEN.
AMINO ACID DEGRADATION.
Chapter 27:Heme Metabolism.
Chapter 28:The Metabolism of Purines and Pyrimidines.
Chapter 29:Vitamins and Minerals.
THE WATER-SOLUBLE VITAMINS.
THE FAT-SOLUBLE VITAMINS.
THE TRACE MINERALS.
Chapter 30:Integration of Metabolism.
HORMONAL REGULATION.
FEEDING AND FASTING
DIABETES MELLITUS.
PHYSICAL EXERCISE.
THE METABOLISM OF XENOBIOTICS.
| 出版社 | 东华大学出版社有限公司 |
|---|---|
| 作者 | 董平军 |